pathway相关论文
30. Knockdown of IGF-IR by Antisense Oligodeoxynucleotide auguments the sensitivity of bladder cance
AND AIM: Transitional cell carcinoma (TCC) of the bladder represents the fifth most prevalent malignancy in Western popu......
Intraseasonal oscillation intensity over the western North Pacific:Projected changes under global wa
本文利用8个CMIP5模式的日资料,预估了RCP4.5和RCP8.5情景下全球增温达1.5℃和2.0℃时西北太平洋夏季30~60天和10~20天季节内振荡(IS......
DNA damage has been linked to neuropathology. Diverse DNA damage response (DDR) pathways help preserve DNA integrity in ......
1.IntroductionrnClimate change is currently the most significant untraditional challenge to human development.Most count......
Role of Cyp19a1 in the female pathway of a freshwater turtle species(Mauremys reevesii)with temperat
The molecular mechanisms underpinning temperature-dependent sex determination(TSD)in reptiles have attracted great biolo......
Detailed research on China\'s CO2 emission pathway of the 2030 peak and 2060 carbon neutrality goals is fun-damental t......
Guanosine-5′-triphosphate cyclohydrolase 1 regulated long noncoding RNAs are potential targets for m
Several studies have confirmed that microglia are involved in neuropathic pain. Inhibition of guanosine-5′-triphosphate......
Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeut
In gliomas,the canonical Wingless/Int (WNT)/β-catenin pathway is increased while peroxisome proliferator-activated rece......
Nanotube is currently among the most promising structures in nanoscience, which exhibits unique properties and holds pro......
The degradation of β-D-glucose in formic acid solutions has been studied.The effects of temperature(55?℃-75?℃)and aci......
Zebrafish (Danio rerio) as a model for the study of infectious reaction against Spring viraemia of c
Spring viraemia of carp (SVC) is a viral disease that causes outbreaks in common carp (Cyprinus carpio) and several othe......
Leptin Regulated the Expression of Cytokines Involving in Embryo Implantation in Primary Porcine End
...
Metabolomicanalysiswasperformedtodeterminethemetabolomicsignatureofosteonecrosisofthefemoralhead(ONFH),andtheunderlyingr......
Knockdown of Akt2suppresses tumorigenesis and Raf1 overexpression offsets this effect in non-small c
目的 Akt2(Protein Kinase B isoform 2)is an essential protein,which is involved in tumor cell proliferation,differentiati......
Formaldehyde influence DNA damage repair process through PARP-1 pathway in the human bronchial epith
OBJECTIVE To investigate the cellular pathways or proteins involved in DNA damage repair induced by low concentration fo......
Objective Gastric cancer(GC)is expected to rank as the fifth most common neoplasms and the second cause of cancer-relate......
Objective Esophageal cancer,a complex disease caused by many risk factors,is one of the most prevalent cancers in the wo......
Network approaches for exploring nutritional adaptations of the psyllid symbionts Candidatus Liberib
Candidatus Liberibacter is a genus of Gram-negative bacteria related to many devastating plant diseases.Except Liberibac......
Identification of candidate genes and pathways underlying drought tolerance and yield potential by g
Drought has become the most important factor limiting rice yield in many areas of rainfed ecosystems of Asia and Africa....
The genome heterogeneity between breast and prostate tumors stromal revealed by a comparative transc
Background: Cancer is complex due to the extensive heterogeneity both between and within tumors.The cancer progression a......
Background: β-thalassemia is caused by β-globin(HBB) gene mutations.However, heterogeneous phenotypes have been found ......
Using a shotgun strategy coupled with high-throughput data mining to map the proteome of normal huma
Physiological processes are often associated with changes in protein expression,post-translational modification,and/or s......
Mycoplasma play important roles in the emerging field synthetic biology due to their small genomes and simple metabolic ......
Identification of candidate genes and pathways underlying drought tolerance and yield potential by c
Drought has become the most important factor limiting rice yield in many areas of rainfed ecosystems of Asia and Africa.......
Background: Identification of differential expressed genes can expose disease disordered pathways.Currently, Most calcul......
Transcriptomics analysis of the Glucose metabolism pathway in the livers of thyroid hormones induced
Object:To investigate potential pathways which can regulate glucose metabolism in the liver tissues of thyroid hormones ......
Purpose: The main purpose of this study was to investigate the active components of the Chinese medicine formula Shenqi ......
Down-regulation of progranulin improve learning and memory in mouse model of fragile X syndrome thro
OBJECTIVE To exhibit the role of PGRN in fragile X syndrome(FXS)cognition disability development.METHODS Expression of P......
Background:The PI3K-AKT pathway is known to regulate cytokines in dust mite-induced pediatric asthma.However,the underly......
慢性肾衰竭(CRF)是因肾单位严重受损而缓慢出现肾功能减退而至衰竭的一组临床综合征。尿毒清主要成份有大黄、黄芪、甘草、茯苓等......
Due to the wide application of microarray technology,enormous amount of gene expression data have been generated for dis......
Multiple myeloma(MM) is an incurable cancer.However,recent advances have been made,which not only enhances understanding......
Sepsis causes neutrophil sequestration in the lung which leads to acute lung injury(ALI).Neutrophil elastase(NE) is thou......
Genome-wide association study knowledge-driven pathway analysis of alcohol dependence implicates the
...
OBJECTIVE To investigate the effect of scutellarin on the apoptosis of human colorectal cancer cells via the Hippo signa......
Inhibitory action of berberine on colorectal cancer HCT116 cells by regulation of Hedgehog signaling
OBJECTIVE To investigate the inhibition and mechanism of berberine on human colorectal cancer HCT116 cells through canon......
OBJECTIVE To investigate the pharmacological effect of ursolic acid(UA)on colitis-associated colorectal cancer(CAC)and i......
Suppression of AOM/DSS-induced colorectal cancer by scutellarin through downregulation of Wnt signal
OBJECTIVE To investigate the therapeutic effect of scutellarin on colitis-associated cancer(CAC)and its underlying mecha......
Chaetocin is a natural metabolite product with various biological activities and pharmacological functions isolated from......
Mechanisms of Cinnamomi Ramulus for coronary heart disease treatment:prediction based on network pha
Chinese medicine.However,little is known about the potential mechanism.Elucidating the effective components and mechanis......
Hepatocellular carcinoma(HCC)is one of the most common malignant tumors in clinical practice.The pathogenesis of HCC is ......
Aspirin-induced long-term tumor remission in hepatocellular carcinoma with adenomatous polyposis col
BACKGROUND Targeted therapy based on pathway analysis of hepatitis B-related hepatocellular carcinoma(HCC)may be a promi......
Promoting bone healing after a fracture has been a frequent subject of research.Recently,sclerostin antibody(Scl-Ab)has ......
Galactose-N/Gr11 inhibits AMPK phosphorylation byactivating the PI3K-AKT-PKF-ATPsignaling cascade vi
As ligands of the sugar gustatory receptors,sugars have been known to activatethe insulin/insulin-like growth factor sig......
Neuritin is a member of the neurotrophic factor family,which plays an important role in the promotion and development of......
BACKGROUND Pancreatic cancer is a highly malignant tumor of the gastrointestinal system whose emerging resistance to che......
Chromosome-level genome of Himalayan yew provides insights into the origin and evolution of the pacl
Taxus,commonly known as yew,is a well-known gymnosperm with great ornamental and medicinal value.In this study,by assemb......
Carvacrol Promotes Cell Cycle Arrest and Apoptosis through PI3K/AKT Signaling Pathway in MCF-7 Breas
Objective:To examine the role of carvacrol in modulating PI3 K/AKT signaling involved in human breast cancer pathogenesi......